General Pathology

Mechanisms of cellular ageing

Role of free radicals in cell injury

Endogenous pigments

Mechanism of cellular aging

Role of oxidative stress in cell injury

Cellular aging and telomere

Sequence of events in hypoxic injury to cells

Role of free radicals in health and disease

Gene therapy

Genomic imprinting

Intracellular accumulations

Ischemia-reperfusion injury

Mechanisms of generation and removal of free radicals

Obesity associated diseases

Proteins involved in signal transduction

Role of telomerase in cellular aging

Signalling mechanisms in cell growth

Telomeres

Warburg effect

Role of adhesion molecules in inflammation

Toll-like receptors

Acute phase reactants

Adhesion molecules in inflammatory response

Chemokines

Chronic granulomatous disease

Defects in leucocyte function

Functions of leukocytes in inflammation and clinical conditions of leukocyte dysfunction

Role of adhesion molecules in inflammation and healing

Role of cytokines in inflammation

Role of arachidonic acid metabolites in inflammation

Role of cytokines and growth factors in tissue regeneration and wound healing

Eicosanoids

Functional leucocyte abnormalities

Inflammatory actions of eicosanoids

Inhibitors of acute inflammation

Mediators of cellular events of acute inflammation

Pathogenesis of granulomatous inflammation

Role of macrophages in wound healing

Role of platelet activating factor in inflammation

Substance P

Role of growth factors in cutaneous wound healing

Mechanism of angiogenesis in wound healing

Role of stem cells in tissue homeostasis

Angiogenesis

Effects of growth factors and their receptors in neoplasia

Mechanisms of angiogenesis in healing and repair

Fracture callus

Functions of TGF in wound healing and repair

Matrix metalloproteinases

Role of angiogenesis in neoplasia

Role of angiogenesis in tissue repair

Role of extracellular matrix in cell growth

Role of matrix metalloproteinases in diseases

Stem cell

Types of collagen and their significance

Pathogenesis of septic shock

Pathophysiology of septic shock

Antithrombotic properties of normal endothelium

Anti-thrombotic properties of endothelium

Stages of shock

Pathogenesis and pathology of septic shock

Role of endothelium in health and disease

Role of endothelium in regulation of homeostasis

Hypercoagulable states

Pathogenesis and complications of thrombosis

Pathogenesis of cardiac edema

Pathogenesis of thrombus formation

Pathophysiology of irreversible shock

Procoagulant activities of endothelium

Risk factors associated with thrombus formation

The endothelial cell in health and disease

Mechanisms of immunologic tolerance

Antibodies in SLE

Antiphospholipid antibody syndrome

Class I MHC molecules

Mechanisms of type IV hypersensitivity reactions

Pathogenesis and criteria for classification of SLE; morphology of renal SLE

Pathogenesis of autoimmune diseases

Mechanisms of autoimmunity and autoimmune endocrine disorders

Mechanisms of self tolerance and autoimmunity

General principles of mechanism of autoimmunity with examples

Immune complex associated vasculitis

Immunological tolerance

Mechanism of autoimmune disease

Mechanism of autoimmunity in SLE

Pathogenesis of autoimmune disorders

Significance of ANCA

Type I hypersensitivity reaction

Mechanism of T cell immunodeficiency in HIV infection

AIDS defining opportunistic infections

Immunopathology of transplant rejection

Factors influencing transplant rejection

Pathophysiology of manifestations of AIDS

Graft versus host disease

Hyper-IgM syndrome

Mechanism of recognition and rejection of allografts

Pathology of graft versus host disease

Role of T cells in transplant rejection

T cell mediated graft rejection

Pathogenesis of amyloidosis

Classification and pathogenesis of amyloidosis

Tumor markers

Cancer cachexia

Cell cycle

Cell cycle with checkpoints; cyclins, CDKs and CDK inhibitors

Role of p53 in tumorigenesis

Sequential steps in metastatic cascade

Microbial carcinogenesis

Molecular basis of tumor development and progression

Pathogenesis of chemical carcinogenesis

Prognostic markers and mechanisms of metastasis

Role of cyclins and CDKs in cell cycle regulation

Role of tumor suppressor genes; epigenetic changes

Role of tumor suppressor genes in development of cancer

DNA mismatch repair genes

EBV in oncogenesis

HPV and genital cancer

Mechanisms of hypercalcemia in malignancy

Micro RNAs and their role in carcinogenesis

Microsatellite instability

miRNA and carcinogenesis

miRNAs in oncogenesis

Oncofetal antigens as tumor markers

Oncogenic DNA viruses

p21

p53

PTEN

Radiation oncogenesis

Role of APC gene in tumorigenesis

Role of cyclins in disease

Role of molecular markers in cancer prognosis

Role of oncogenic DNA viruses in neoplasia

Role of p53 gene in neoplasia

Role of RAS oncogene in human tumors

Role of retinoblastoma gene in neoplasia

Role of stroma in tumor progression

Tumour immunity

VHL gene

Viral oncogenesis

Mechanism of apoptosis with diagram

Sequence of events in a dying cell

Apoptosis and its role in health and disease

Mitochondrial pathway of apoptosis

Morphological and biochemical changes in apoptosis

Classification of lysosomal storage disorders

Gaucher disease

Techniques in molecular diagnosis of genetic disorders

Role of molecular diagnostic tests in genetic disorders

Lysosomal storage diseases; features of Gaucher's disease

Molecular biology of Gaucher's disease

Turner syndrome

Types of Niemann-Pick disease

Cytomegalovirus infection in humans

Pathogenesis of complications of diabetes mellitus

Pathogenesis of tuberculosis

Vitamin D deficiency

Mechanism of auto-immunity

Morphological consequences of radiation injury

Liquid based cytology

Quality assurance in cytology

Application of frozen section in histopathology

Automation in cytology

Bronchial brush cytology and its utility

Crush smear cytology of glial tumours

Cytocentrifugation

Cytopreparatory techniques and staining of effusions

Role of immunofluorescence in renal pathology

Fixatives in cytology

Immunocytochemistry in tumor diagnosis

Polarising microscopy

Preparation and utility of cell block technique

Processing of mucoid fluids in cytology

Quality assurance in cytology lab

Saccommanno's technique

Squash technique in CNS tumors

Technique of liquid based cytology

Bethesda system for reporting thyroid cytopathology

Atypical glandular cells in cervical cytology

Bethesda system in gynecologic cytology

Cervical cytology in postmenopausal women

CSF cytology in neoplastic meningitis

Cytologic features of medullary carcinoma thyroid & DD

Cytological evaluation of malignant ascites

Cytological workup of solitary thyroid nodule

Cytology of follicular neoplasms of the thyroid

Cytology samples in pulmonary lesions

Role of FNAC in breast lump evaluation

Role of FNAC in lung lesions

Role of IHC & molecular biology in cytology of MSRCT

Fine needle aspiration techniques in thyroid

Intraoperative cytology in pancreatic lesions

IUD-associated cellular changes in cervical cytology

Pancreatic cytology

Role of FNA in cystic lesions of neck

Role of liquid biopsy in tumor diagnosis

Bethesda system for reporting cervical cytology

Bethesda system for reporting thyroid cytology