⚠ Must-Read List

50 Important Questions

The 50 questions with the highest probability of appearing in the 2026 MD Pathology exam. If you only have time for one list — make it this one.

must-read questions

41%

avg. likelihood

80%

top question

1
LE×8
Mechanism of apoptosis with diagram
Paper I · Apoptosis & Programmed Cell Death
Apr 2017Apr 2018Jun 2020Oct 2020May 2021Oct 2022Jul 2025Nov 2025
📈80% 2026
2
LE/SN×5
Classification and pathogenesis of amyloidosis
Paper I · Amyloidosis & Deposition Diseases
Jun 2020Oct 2020Oct 2022Nov 2025Jul 2025
📈57% 2026
3
LE×5
Prognostic and predictive factors of breast cancer
Paper II · Breast
Oct 2017Jul 2025Apr 2019Jan 2025Oct 2022
📈57% 2026
4
LE×5
Mechanisms of cellular ageing
Paper I · Cell Injury, Adaptation & Cellular Ageing
Apr 2015Oct 2019Jul 2025Apr 2022Dec 2023
📈54% 2026
5
SN×5
Primary carcinomas of salivary gland
Paper II · Salivary Glands / Head & Neck
Oct 2021Jun 2024Oct 2015Apr 2017Oct 2020
📈54% 2026
6
SN×5
Measurable / minimal residual disease
Paper III · Acute Leukemias
Apr 2016Oct 2022Dec 2023Jan 2025Jul 2025
📈54% 2026
7
LE/SN×4
Classify plasma cell dyscrasias; lab diagnosis of MM
Paper III · Plasma Cell Dyscrasias
Oct 2022Jul 2023Oct 2015Jul 2025
📈54% 2026
8
LE/SN×4
Automated cell counters
Paper III · Automation / Instrumentation
Oct 2019May 2021Apr 2022Jul 2025
📈49% 2026
9
LE×4
Quality assurance in blood banking
Paper III · Blood Banking
Apr 2016Apr 2015Jan 2025Jul 2025
📈47% 2026
10
SN×4
Platelet transfusion / SDP
Paper III · Blood Banking
Apr 2017Oct 2021Apr 2022Jun 2024
📈47% 2026
11
SN×4
Bethesda system for reporting thyroid cytopathology
Paper I · Cytopathology – Organ-specific / FNAC / Bethesda
Apr 2019Jul 2025Jan 2025Apr 2017
📈45% 2026
12
LE×4
IHC and DD of GIST
Paper II · Gastrointestinal Tract
Jul 2025Apr 2019Oct 2021May 2021
📈45% 2026
13
SN×4
Non-neoplastic / serrated colonic polyps; familial syndromes
Paper II · Gastrointestinal Tract
Jun 2020Jun 2024Oct 2020Apr 2018
📈45% 2026
14
LE×4
Type 2 DM pathogenesis & complications
Paper II · Endocrine - Other
Jul 2025Oct 2020Apr 2019Apr 2015
📈45% 2026
15
LE×4
Vesiculobullous skin lesions; IF patterns
Paper II · Skin - Non-neoplastic
Nov 2025Apr 2017Oct 2021Apr 2019
📈45% 2026
16
LE×4
Giant cell rich lesions of bone
Paper II · Bone
Nov 2025Jan 2025Oct 2022Jul 2023
📈45% 2026
17
SN×4
Automation in urinalysis
Paper III · Urine & Renal Laboratory Medicine
Apr 2015Jun 2020Jan 2025Jul 2025
📈45% 2026
18
SN×5
Tissue microarray
Paper IV · IHC, Molecular & Ancillary Techniques
Apr 2022Oct 2021May 2021Jul 2023Apr 2017
📈44% 2026
19
LE×3
Molecular classification / non-invasive urothelial neoplasms
Paper II · Urinary Bladder
Nov 2025Jul 2023Oct 2019
📈41% 2026
20
LE×3
Pathogenesis & pathology of GTD
Paper II · Gestational Trophoblastic Disease
Apr 2018Jul 2025Oct 2022
📈41% 2026
21
SN×3
Intermediate / epithelioid / PSTT trophoblastic tumors
Paper II · Gestational Trophoblastic Disease
Oct 2015Jun 2024Apr 2015
📈41% 2026
22
SN×3
Polycythemia vera
Paper III · Myeloproliferative Neoplasms
Oct 2015May 2021Jan 2025
📈41% 2026
23
SN×3
bcr-abl / Philadelphia chromosome
Paper III · Myeloproliferative Neoplasms
Oct 2017Apr 2022Jul 2025
📈41% 2026
24
LE×4
Classify and discuss vasculitis
Paper II · Vasculitis
May 2021Apr 2016Apr 2022Apr 2018
📈40% 2026
25
LE/SN×4
Flow cytometry — principles & applications
Paper III · Automation / Instrumentation
Oct 2015Apr 2017May 2021Dec 2023
📈40% 2026
26
LE×4
Pathogenesis / latest developments in atherosclerosis
Paper II · Cardiovascular System
Apr 2015Apr 2022Oct 2022Dec 2023
📈38% 2026
27
LE/SN×4
Blood component preparation & uses
Paper III · Blood Banking
Oct 2015Oct 2017Jun 2020Dec 2023
📈38% 2026
28
SN×4
Apheresis / plasmapheresis
Paper III · Blood Banking
Apr 2016Apr 2018May 2021Oct 2022
📈38% 2026
29
LE/SN×4
Lysosomal storage diseases; features of Gaucher's disease
Paper I · Genetic & Metabolic Disorders
Oct 2020Apr 2022Oct 2017Oct 2019
📈36% 2026
30
SN×4
Technique of liquid based cytology
Paper I · Cytopathology – Techniques & Quality
Oct 2021Oct 2022Dec 2023Oct 2015
📈36% 2026
31
SN×3
Pathogenesis & morphology of cardiomyopathies
Paper II · Cardiovascular System
Apr 2017Apr 2018Jul 2025
📈36% 2026
32
SN×3
Anterior mediastinal mass / thymoma
Paper II · Respiratory System
Jul 2025Oct 2021Apr 2016
📈36% 2026
33
SN×4
Pathogenesis of HCC; precursor lesions; fibrolamellar HCC
Paper II · Hepatobiliary
Apr 2022Jul 2023May 2021Apr 2019
📈36% 2026
34
LE×3
Endometrial neoplasms; molecular classification
Paper II · Uterus / Endometrium
Apr 2016Jul 2023Jan 2025
📈36% 2026
35
LE×4
Flow cytometry — principle & applications
Paper IV · IHC, Molecular & Ancillary Techniques
Oct 2017Oct 2020May 2021Apr 2022
📈36% 2026
36
LE×3
Role of adhesion molecules in inflammation and healing
Paper I · Acute & Chronic Inflammation
Apr 2016Nov 2025Oct 2022
📈34% 2026
37
LE×3
Pathophysiology of septic shock
Paper I · Haemodynamic Disorders, Thrombosis & Shock
Apr 2016Apr 2019Nov 2025
📈34% 2026
38
LE×3
Mechanism of T cell immunodeficiency in HIV infection
Paper I · Transplantation & Immunodeficiency
Jun 2020Jun 2024Jul 2025
📈34% 2026
39
LE/SN×3
Quality assurance in cytology lab
Paper I · Cytopathology – Techniques & Quality
Oct 2017May 2021Jul 2025
📈34% 2026
40
SN×3
Ductal adenocarcinoma; mimics; IHC in problematic prostate biopsies
Paper II · Prostate
Jan 2025Oct 2017Oct 2015
📈34% 2026
41
SN×3
Skin biopsy in leprosy / histoid leprosy
Paper II · Skin - Non-neoplastic
Jun 2024Jan 2025Oct 2021
📈34% 2026
42
SN×3
Pathogenesis / morphology of Alzheimer's disease
Paper II · Central Nervous System
Jul 2025Jun 2020Oct 2015
📈34% 2026
43
LE/SN×3
Small blue round cell tumors of soft tissue
Paper II · Soft Tissue
Oct 2021Jul 2025Apr 2016
📈34% 2026
44
LE/SN×3
Classification & lab diagnosis of MDS
Paper III · Myelodysplastic Syndrome
Oct 2017Apr 2022Jul 2025
📈34% 2026
45
SN×3
Hairy cell leukemia
Paper III · Chronic Lymphoid Leukemias / Lymphomas
Oct 2019Apr 2019Jan 2025
📈34% 2026
46
LE/SN×3
Microalbuminuria detection
Paper III · Urine & Renal Laboratory Medicine
Apr 2016Apr 2017Nov 2025
📈34% 2026
47
SN×3
IgG4 related diseases
Paper IV · Infectious & Inflammatory
Jul 2025Oct 2020Oct 2017
📈34% 2026
48
SN×3
CISH vs FISH
Paper IV · IHC, Molecular & Ancillary Techniques
Jul 2025Jul 2023Apr 2022
📈34% 2026
49
SN×3
Cystic diseases / cystic neoplasms of pancreas
Paper II · Pancreas
Oct 2015Apr 2017Oct 2022
📈31% 2026
50
SN×3
Antiphospholipid syndrome
Paper III · Coagulation Laboratory Tests
Apr 2015May 2021Apr 2022
📈31% 2026